Identifying Red Flags and Patterns for Hereditary Cardiovascular Disease (CNE)

Assessing the personal and family history of patients with cardiac conditions can lead to a new diagnosis, identify personalized management and treatment options, and provide risk information for family members. In this course, you will practice assessing risk for a genetic cardiac condition, including identifying red flags and patterns in the personal and family history. This course is part of a series, Implementing Cardiogenomics in Clinical Practice.

To claim credit, follow the steps in the learning path.

CNE Information and Disclosures 

Jointly Provided by The Jackson Laboratory and Northwestern University Feinberg School of Medicine Office of Continuing Medical Education.

Original Release Date: February 1, 2023  
Expiration Date: January 27, 2025    

Target Audience  
This activity is designed to meet the educational needs of practicing nurses and advanced practice nurses. 

Learning Outcome
Identify and manage individuals at increased genetic risk of cardiovascular disease due to familial factors and hereditary cardiac syndromes.  

CNE Approval Statement 
This nursing continuing professional development activity was approved by the Northeast Multistate Division Education Unit, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation. 

Nurses are eligible for a maximum of .5 contact hours upon the completion of this activity.

Planners, Writers, Reviewers 

• Lisa Castillo, MS, CGC - Northwestern University 
• Kristen DeBerg, MS, CGC - Sanford Health 
• Emily Edelman, MS, CGC - The Jackson Laboratory 
• Jennifer Gerth, RN, BSN - Northwestern University
• Therese Ingram, MA - The Jackson Laboratory
• Kalisi Logan, MS, CGC - The Jackson Laboratory
• Laura Rasmussen-Torvik, PhD, MPH - Northwestern University
• Greg Webster, MD, MPH - Northwestern University 

Conflict of Interest Disclosure 
This educational activity does not include any content that relates to the products and/or services of a commercial interest that would create a conflict of interest. Unless otherwise noted, the program planners and faculty do not have a financial interest/arrangement or affiliation with any organizations that could be perceived as a real or apparent conflict of interest in the context of the subject of this course. 

The following disclosures are reported that could be perceived as a real or apparent conflict of interest in the education program: Emily Edelman received salary support from Pfizer Inc. through an unrestricted quality improvement grant that focuses on improving ascertainment of hereditary breast cancer, provided by the American Community Cancer Centers and Pfizer Independent Grants for Learning & Change. Kalisi Logan served on the Scientific Advisory Board for Igentify. In their roles as planners and content authors, Ms. Edelman and Ms. Logan recused themselves from all deliberations relating to content related to the commercial entity with which they have financial interest and were not responsible for reviewing for bias any related content. All educational material has been peer-reviewed by external reviewers to assess for bias. 

Commercial Support  
This program was supported by educational grants from the American Heart Association. There is no commercial support being received for this activity.   

References 
Hershberger RE, Givertz MM, Ho CY, et al. Genetic Evaluation of Cardiomyopathy-A Heart Failure Society of America Practice Guideline. J Card Fail. 2018;24(5):281-302.  

Ingles J, Macciocca I, Morales A, Thomson K. Genetic Testing in Inherited Heart Diseases. Heart Lung Circ. 2020;29(4):505-511. 

Landstrom AP, Kim JJ, Gelb BD, et al. Genetic Testing for Heritable Cardiovascular Diseases in Pediatric Patients: A Scientific Statement From the American Heart Association. Circ Genom Precis Med. 2021;14(5):e000086.  

Lopez Santibanez Jacome L, Dellefave-Castillo LM, Wicklund CA, et al. Practitioners' Confidence and Desires for Education in Cardiovascular and Sudden Cardiac Death Genetics. J Am Heart Assoc. 2022;11(7):e023763. 

Middleton O, Baxter S, Demo E, et al. National Association of Medical Examiners Position Paper: Retaining Postmortem Samples for Genetic Testing. Academic Forensic Pathology. 2013;3(2):191-194. 

Musunuru K, Hershberger RE, Day SM, et al. Genetic Testing for Inherited Cardiovascular Diseases: A Scientific Statement From the American Heart Association. Circ Genom Precis Med. 2020;13(4):e000067. 

Ommen SR, Mital S, Burke MA, et al. 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines [published correction appears in Circulation. 2020 Dec 22;142(25):e633]. Circulation. 2020;142(25):e558-e631. 

Scherr CL, Kalke K, Ramesh S, et al. Integrating clinical genetics in cardiology: Current practices and recommendations for education. Genet Med. 2022;24(5):1054-1061.  

Stiles MK, Wilde AAM, Abrams DJ, et al. 2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families. Heart Rhythm. 2021;18(1):e1-e50.  

Yoneda ZT, Anderson KC, Quintana JA, et al. Early-Onset Atrial Fibrillation and the Prevalence of Rare Variants in Cardiomyopathy and Arrhythmia Genes. JAMA Cardiol. 2021;6(12):1371-1379.  

Hardware/Software Requirements

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Screen resolution of 800X600 or higher 
Adobe Reader 5.0 or higher 

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Should you have questions about CME approval, contact the Feinberg School of Medicine Office of Continuing Medical Education.

Disclaimer 

All information in Implementing Cardiogenomics in Clinical Practice is provided for educational purposes only. This information is not a substitute for clinical guidance or the consultation of a medical professional. Always seek the advice of a qualified health professional with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read in Implementing Cardiogenomics in Clinical Practice. Reliance on any information in Implementing Cardiogenomics in Clinical Practice is solely at your own risk. The Jackson Laboratory does not endorse or recommend any specific procedures, tests, products, services, health professionals or other information that may be found in Implementing Cardiogenomics in Clinical Practice.