Identifying Red Flags and Patterns for Hereditary Cardiovascular Disease (CME)

Assessing the personal and family history of patients with cardiac conditions can lead to a new diagnosis, identify personalized management and treatment options, and provide risk information for family members. In this course, you will practice assessing risk for a genetic cardiac condition, including identifying red flags and patterns in the personal and family history. This course is part of a series, Implementing Cardiogenomics in Clinical Practice.

To claim credit, follow the steps in the learning path.

CME Information and Disclosures 

Jointly Provided by The Jackson Laboratory and Northwestern University Feinberg School of Medicine Office of Continuing Medical Education.

Release Date: February 1, 2023 
Expiration Date: February 1, 2026  

Learning Objectives

• Identify red flags that increase genetic cardiac risk
• Identify patterns that increase genetic cardiac risk 

Target Audience 
Practicing cardiology physicians, physician assistants, and nurses. 

Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Northwestern University Feinberg School of Medicine and The Jackson Laboratory. Northwestern University Feinberg School of Medicine is accredited by the ACCME to provide continuing medical education for physicians.  

Credit Designation Statement
Northwestern University Feinberg School of Medicine designates this enduring material for a maximum of .5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Disclosure
FSM’s CME Leadership and Staff have nothing to disclose.

Course Director’s and Planning Committee Members Disclosure Information:
Lisa Castillo, MS, CGC - Northwestern University - Has nothing to disclose.
Kristen DeBerg, MS, CGC - Sanford Health - Has nothing to disclose.
Emily Edelman, MS, CGC - The Jackson Laboratory - Supported on grant from Pfizer Inc. (relationship has ended)
Jennifer Gerth, RN, BSN - Northwestern University - Has nothing to disclose.
Therese Ingram, MA - The Jackson Laboratory - Has nothing to disclose.
Kalisi Logan, MS, CGC - The Jackson Laboratory - Serves as an advisor for Igentify.
Laura Rasmussen-Torvik, PhD, MPH - Northwestern University - Has nothing to disclose.
Greg Webster, MD, MPH - Northwestern University - Has nothing to disclose.

All of the relevant financial relationships listed for these individuals have been mitigated.

This activity is being sponsored by the Feinberg School of Medicine, Department of Preventive Medicine and The Jackson Laboratory.  The medical school has no significant relationship with the commercial companies whose products are services are being discussed in this educational activity. The program does not discuss the off-labeled use of any product. 

Educational Support 
This program was supported by educational grants from the American Heart Association. There is no commercial support being received for this activity.  

References 
Hershberger RE, Givertz MM, Ho CY, et al. Genetic Evaluation of Cardiomyopathy-A Heart Failure Society of America Practice Guideline. J Card Fail. 2018;24(5):281-302.  

Ingles J, Macciocca I, Morales A, Thomson K. Genetic Testing in Inherited Heart Diseases. Heart Lung Circ. 2020;29(4):505-511. 

Landstrom AP, Kim JJ, Gelb BD, et al. Genetic Testing for Heritable Cardiovascular Diseases in Pediatric Patients: A Scientific Statement From the American Heart Association. Circ Genom Precis Med. 2021;14(5):e000086.  

Lopez Santibanez Jacome L, Dellefave-Castillo LM, Wicklund CA, et al. Practitioners' Confidence and Desires for Education in Cardiovascular and Sudden Cardiac Death Genetics. J Am Heart Assoc. 2022;11(7):e023763. 

Middleton O, Baxter S, Demo E, et al. National Association of Medical Examiners Position Paper: Retaining Postmortem Samples for Genetic Testing. Academic Forensic Pathology. 2013;3(2):191-194. 

Musunuru K, Hershberger RE, Day SM, et al. Genetic Testing for Inherited Cardiovascular Diseases: A Scientific Statement From the American Heart Association. Circ Genom Precis Med. 2020;13(4):e000067. 

Ommen SR, Mital S, Burke MA, et al. 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines [published correction appears in Circulation. 2020 Dec 22;142(25):e633]. Circulation. 2020;142(25):e558-e631. 

Scherr CL, Kalke K, Ramesh S, et al. Integrating clinical genetics in cardiology: Current practices and recommendations for education. Genet Med. 2022;24(5):1054-1061.  

Stiles MK, Wilde AAM, Abrams DJ, et al. 2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families. Heart Rhythm. 2021;18(1):e1-e50.  

Yoneda ZT, Anderson KC, Quintana JA, et al. Early-Onset Atrial Fibrillation and the Prevalence of Rare Variants in Cardiomyopathy and Arrhythmia Genes. JAMA Cardiol. 2021;6(12):1371-1379.  

Hardware/Software Requirements

Audio speakers or headphones 

Screen resolution of 800X600 or higher 
Adobe Reader 5.0 or higher 

Check the supported browsers. 

Should you have questions about CME approval, contact the Feinberg School of Medicine Office of Continuing Medical Education.

Disclaimer 

All information in Implementing Cardiogenomics in Clinical Practice is provided for educational purposes only. This information is not a substitute for clinical guidance or the consultation of a medical professional. Always seek the advice of a qualified health professional with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read in Implementing Cardiogenomics in Clinical Practice. Reliance on any information in Implementing Cardiogenomics in Clinical Practice is solely at your own risk. The Jackson Laboratory does not endorse or recommend any specific procedures, tests, products, services, health professionals or other information that may be found in Implementing Cardiogenomics in Clinical Practice.